A Novel Live Pichinde Virus-Based Vaccine Vector Induces Enhanced Humoral and Cellular Immunity after a Booster Dose

A Novel HIV Vaccine Adjuvanted by IC31 Induces Robust and Persistent Humoral and Cellular Immunity

The HIV vaccine strategy that, to date, generated immune protection consisted of a prime-boost regimen using a canarypox vector and an HIV envelope protein with alum, as shown in the RV144 trial. Since the efficacy was weak, and previous HIV vaccine trials designed to generate antibody responses failed, we hypothesized that generation of T cell responses would result in improved protection. Thu...

Effects of measles vaccine on humoral and cellular immunity

• Vol 10 • August-September 2008 640 Measles is still a significant cause of morbidity and mortality in children in the Middle East. This region has many hard-to-reach populations, causing difficulties in the provision of adequate immunization coverage. There has been concern that measles vaccine may produce transient immunosuppression in malnourished children and thereby increase their risk fo...

Studies on the Duration of Immunity conferred by a Live Modified Sheep Pox Tissue Culture Virus Vaccine

Humoral and cellular immune responses to a hepatitis B vaccine booster 15-18 years after neonatal immunization.

BACKGROUND Whether hepatitis B (HB) vaccine-conferred immunity persists into adulthood is unknown. We aimed to investigate long-term HB immunity in adolescents. METHODS In 2004-2005, 6156 high school students (15-21 years old) who had been vaccinated with plasma-derived HB vaccine as infants were recruited for HB seromarker screening. The immune response to an HB vaccine booster was evaluated...

Cellular and Humoral Immunity

The Abstract was presented at the Fourth Herpes Virus Meeting, Cold Spring Harbor, N. Y. Dr. Pollard's present address is Division of Infectious Diseases, University of Texas Medical Branch, Galveston, Texas. Received for publicatiotn 2 October 1979 anid inl revised forimi 14 December 1979. recovery of phytohemagglutinin transformation often preceded recovery of the responses to viral antigens....